Finance is the core of modern economy and promoting the industry innovation through finance is one of the important contents of the strategy of China’s“developing the country through science and education”. This paper discusses the theory and mechanism of promoting industry innovation development through finance from the perspective of crossregional capital investment effect, resource allocation discrimination effect, growth span effect and industrial innovation development effect. Based on a comprehensive analysis of the present situation of the Yangtze economic zone including crossregional industry development through finance, hierarchical development of regional financial center construction and crossregional industry coordination development, this paper puts forward the strategic idea of promoting the coordination development of industrial innovation in the Yangtze economic zone on the basis of coordination development of financial center construction.