According to the special cement type, water-to-cement ratio, mix proportion, and particle size distribution of aggregates, the CEMHYD3D hydration model was used to rebuild the representative volume element(RVE)model of a microstructure(cement)based on the micro scale, and the hard core/soft shell model was developed to build the RVE model of the mesostructure based on the meso scale. Then, numerical homogenization methods based on the Rankine criterion and the damage model, which are respectively suitable for mico and meso scales, were studied. Hierarchical analysis and prediction methods for concrete mechanical properties are proposed. The results of an example show that the proposed method can satisfactorily analyze and predict the macro mechanical properties of concrete. The developed reconstruction microstructure method can also be used to explore the aging and degradation mechanisms for concrete with simulations of physical and chemical processes at a micro scale.