From the theory of exquisite financial management, the current states and challenges of financial management of scientific and technological projects of Jiangsu Water Source Company are introduced based on its basic situations. The necessity to improve the level of exquisite financial management of scientific and technological projects is expounded. On this basis, a set of exquisite financial management system of scientific and technological projects is proposed for Jiangsu Water Source Company, which is composed of strategic level, institutional layer, business level, evaluation level and virtual level.