As an important part of the flood control system, the flood detention zone plays an important role in mitigating the flood pressure on the embankments of Huaihe River. Using the flood detention zones will cause various risks such as economic losses, casualties and environmental pollution. The risk of using flood detention zones is the result of the common action of the factors which are potential of disaster factors, vulnerability of environment and disasters as well as frangibility of disaster prevention system. The risk factors of using flood detention zones are analyzed from four aspects, and the relevant risk control strategies are proposed.