Based on the study of Water-Oriented Development model, this paper discusses the Water-Oriented Development model, and puts forward the concept of Water-Oriented Development (WOD), that is, the regional comprehensive development model oriented to the development, utilization and protection of water resources. This paper analyzes its connotation and typical characteristics, carries out feasibility analysis, probes into the implementation path of WOD, and proposes relevant suggestions. Under the guidance of adhering to the“Maximum rigid constraint of water resources” and the concept of regional sustainable development, we should popularize and practice the WOD model in time, it is suggested that the comprehensive management of water environment and the comprehensive development and utilization of water resources should be taken as the leading factors and primary tasks for the green development of water-related areas, which is a beneficial exploration for the realization of the value of water ecological products, it also provides a new idea for realizing the harmonious unification of regional economic development and natural environment.