In order to study the pollutant flux sharing rate of different administrative areas in the Qinhuai River, the pollutant flux of the main pollutants(NH₃-N and TP)into the Qinhuai River influencing by the tributaries and sewage pumping stations in 2016 were simulated based on the one-dimensional plain river network water environment mathematical model. Combined with the measured and calculated results, quantitative analysis of the pollutant flux sharing rate of different control units and administrative areas in the whole basin was carried out. The results show that the pollutant sharing rates of different administrative areas in the Qiqiaoweng section are as follows: the average sharing rates of NH₃-N and TP of Qinhuai District are 12% and 13%, respectively; the average sharing rates of NH₃-N and TP of Yuhuatai District are 20% and 15%, respectively; the average sharing rate of NH₃-N of Jianye District is 2%; the average sharing rates of NH₃-N and TP of Jiangning District are 55% and 53%, respectively; the average sharing rates of NH₃-N and TP of Lishui are 1% and 2%, respectively; the average sharing rates of NH₃-N and TP of Jurong City are 10% and 17%, respectively.