To discuss the influence of load conditions on the topology optimization for RC deep beams, and improve their current design methods as well, in this paper the optimal topology structures for RC deep beams with openings under different concentrated loading conditions and different load concentration conditions were separately evolved based on the evolutionary topology optimization algorithm. Then, the corresponding StrutandTie models were constructed according to these optimal topology structures. The diversities among these optimal topology structures and among these StrutandTie models were discussed next. The results show that all these StrutandTie models conform better to Michell structures which have full stress distribution. The loads are always transmitted from the loading point to the support in the form of pressure through the shortest straight struts when a concentrated load is applied on the top surface of the beams, while the loads are suspended on the main pressure arch by umbrella shaped ties and then transmitted to the support when a concentrated load is applied on the web or bottom of the beams. The optimal topological structures always evolve into arch structures or hybrid system of archandcompositestrut as the load concentration decreases, especially those are close to uniform loads applied on the beam. Furthermore, the RC deep beams under different load conditions may be designed with some hidden reinforced compression parts and tensile reinforcements in beam body by the light of the optimal topology structures in engineering designs.