Taking the Meiliang Bay of Lake Taihu as the research object, to investigate the effect of Bellamya aeruginosa degradation on the migration characteristics of tungsten in sediments, the planar optobe technique was used to measure the two-dimensional plane distribution of dissolved oxygen (DO) in sediment-water interface, and the High-resolution Peeper (HR-Peeper) and Diffusive Gradients in Thin Films (DGT) technique were used to analysis the one-dimensional vertical distribution information of dissolved/biological labile tungsten (W) concentration. The results showed that Bellamya aeruginosa decomposition significantly reduced the dissolved oxygen (DO) concentration in the sediment-water interface. Anaerobic conditions formed by degradation caused the concentration increase of dissolved tungsten in the interstitial water and the overlying water. The average concentration of dissolved W in sediments profile increased by 28.92%～114.46% compared with that in the control group and the bioavailability of tungsten at the sediment-water interface was significantly improved according to results measured by the DGT. Similar to tungsten concentration changes, the concentration of iron and manganese also increased significantly during B. aeruginosa decomposition (Day 8), and the change of iron and manganese was significantly positively associated with the concentration change of tungsten (R2≥0.716 and p<0.01), which indicated that the increase of dissolved tungsten concentration was mainly due to the reduction and dissolution of iron-manganese oxides under anaerobic conditions. On days 16 and 36 of degradation, the accumulated tungsten release from B. aeruginosa caused an increase in the tungsten concentration.