In view of fewer drilling wells and the difficulty of thin reservoir prediction in the rolling exploration stage in an area in Huizhou, the pre-stack simultaneous inversion technique based on the regularization operator was adopted to solve the problems of the difficulty of determining the lateral boundary of sand using the skewed distribution of drilling. More reasonable variation and variation functions were determined and treated as the key parameter input for geo-statistics inversion. The predicted thickness of the vertical thin reservoir was improved by geo-statistical inversion. The inversion results show that the reservoir in the design well X3 will develop, and data from the new drilling well X3 verify the result. There are three sets of sand bodies in the target zone: A2UP, A2LOW, and A2, which are mutually unconnected.