To summarize the occurrence regularity and characteristics of sudden siltation during typhoon period in the deepwater navigation channel of Yangtze Estuary, the meteorological conditions and corresponding wave conditions during sudden siltation are analyzed. The results show that the wave energy correlates well with the siltation in NPJ station. The analysis of typhoon paths suggests that the sudden siltation in the navigation channel is significantly influenced by the taphoon passing through the east part of Yangtze Estuary. In this study, three typical typhoon paths are selected with reference to the historic typhoon paths in Yangtze Estuary, and the typhoon field was replicated by combing the empirical circular(Fujita and Takahashi)wind field and CFSR(climate forecast system reanalysis)wind field. SWAN model is then used to simulate the wave conditions under different typhoons paths. Finally, the effects of different typhoon paths on the sudden siltation are analyzed by taking the shallow water wave energy in NPJ station as the discriminant parameter. The study indicates that the typhoon passing through the east area of the Yangtze Estuary is found to be a typical typhoon path, which can readily induce relatively large wave energy and subsequent sudden siltation. And such analysis result agrees well with that of measured typhoon path causing sudden siltation since 2010.