According to the hydrogeological conditions and characteristics of groundwater movement of agricultural irrigation area in Fuyang City, China, this paper proposed a regional long-term combined regulation model of shallow grandwater. By regulating the groundwater exploitation, the depth to water table at the end could be restored to the beginning, achieving the long-term balance. Then, the safe exploiting coefficient and the safe exploitation quantity are obtained. The results based on a long series(1956-2010) show that the average total recharge of shallow groundwater is 17.856×10⁸m³, the safe exploiting coefficient is 0.469, and the safe exploitation quantity is 8.374×10⁸m³. Combining with the water using characteristics of agricultural irrigation area in Fuyang City, the method of equal proportion is applied to calculate the annual distribution of the safe exploitation quantity of shallow groundwater. Finally, it is determined the monthly safe exploiting processs of shallow groundwater within one year in Fuyang City.