In order to improve the refinement degree of the quality control of slope excavation for hydropower stations and realize the informatization management, large amount of high precise point cloud data obtained by three-dimensional(3D) laser scanning was applied into the quality control of slope excavation. Based on the quality control theory of slope excavation and the comprehensive analysis of users’ demands, a quality control system of slope excavation for hydropower stations is designed and developed using the structure modular design method and software development technology. This system consists of five modules: data entering, data analysis of excavated surface, profile analysis of excavated surface, accident query, and statistical reports. The proposed system can provide real-time, dynamic, and interactive query of quality control information during the whole process of slope excavation. The results based on practical application show that this system can provide information for quality control and field management of slope excavation and assist engineers to take relevant quality control measures in time.