Aiming at the lack of geological and hydrological data, a stability analysis method for the reservoir slopes is proposed. First, the overall geotechnical properties of the slopes are extracted using the remote sensing technology, and then the detailed geological data for the slopes is derived through an inversion model based on the monitoring data of a certain slope with deformation and failure. Finally, the deformation of each individual slope can be traced and predicted by the coupling analysis model. This method has been applied to the stability analysis of typical slopes in the Three Gorges Reservoir Region, and the results show that the predicted displacement and direction of the landslide mass basically agrees with field observation. The predicted trajectory direction of the main landslide tendency also agrees well with observation.