In order to study the problem of site vibration induced by flood discharge of high dams, a method combining finite element numerical simulation and hydraulic model test is proposed to calculate the site vibration response. Taking a domestic project as an example, the vibration response of the concerned area under different working conditions was calculated. The influence of flood discharge and flood discharge scheduling mode on the site vibration was analyzed, and the propagation law of vibration wave under different rock conditions was revealed. The results show that the life of the surrounding residents cannot be affected by any kinds of flood discharge methods of the project. The larger the discharge, the greater the vibryation response of the downstream site can be. When the flood discharge conditions of the three spillway tunnels are the same, the No. 2 tunnel discharge is the most unfavorable. Under the same flood discharge conditions, the vibration response of the four tunnels is less than that of the designed opening. The main reason for amplifying the vibration wave in the model range is the difference nature of the rock mass around the fault, the existence of faults further increases the amplification effect.