In order to further understand the bond behavior of FRP-concrete interface in underground gas storage under combined compression and shear conditions, an indoor direct shear test was conducted to study the bond performance of the FRP-concrete interface under varying influencing factors, including normal stress, concrete surface roughness, adhesive thickness and concrete strength. The results show that the FRP-concrete interface is mainly characterized by debonding failure of the concrete surface under the combined compression and shear conditions. A significant nonlinear relationship exists between the interfacial shear stress and displacement. The strength and stiffness of the interface increase with the increase of normal stress, concrete surface roughness, adhesive thickness and concrete strength. The Mohr-Coulomb criterion can be used to describe the yield failure behavior of the interface under compression and shear conditions.