Based on the three-dimensional numerical model for Lingdingyang Bay of the Pearl River network, the tidal energy flux and dissipation in Lingdingyang Bay under effects of strong wind were analyzed with the method of integration of regional energy dissipation. Results show that the tidal energy transfers into Lingdingyang Bay and the Pearl River Delta through the deep channel. The effects of wind lead to the changes in the amplitude and phase of the tidal energy flux in Lingdingyang Bay, while have insignificant influence on the average energy flux of multiple tides through each cross-section. Strong wind increases the tidal energy dissipation per unit area in Lingdingyang Bay, and the vertical eddy turbulence energy dissipation increases by 1~2 times; however, it does not produce a great change in friction-induced energy dissipation and does not change the spatial distribution of energy dissipation under the effects of landform’s resistances.