According to river health assessment methods,an index system of health assessment on Guanlan River were set up by adopting analytic hierarchy process, and a method of comprehensive index was used to evaluate the health state of Guanlan River before and after its comprehensive treatment. The result shows that the upstream and midstream of Guanlan River is in the unhealthy condition and its downstream is in the sub health state before the Guanlan River comprehensive treatment, while the upstream and downstream of Guanlan River in the sub healthy state and its midstream in the healthy state after the Guanlan River comprehensive treatment. The river ecosystem presents positive succession trend after the Guanlan River comprehensive treatment, but there is still a certain degree anthropogenic interference in Guanlan River.