Problems in traditional methods for treating cyanobacteria bloom were pointed out, which is algal cells rupture will happen when killing massive cyanobacteria, and intracellular algal toxins and other harmful secretions are inevitably released to the aquatic environment, leading to the secondary pollution. Therefore, the preventive regulation method for cyanobacterial blooms was proposed in this study. Before cyanobacterial blooms happen, algae biomass was herein controlled under a certain level by inhibiting algae growth. Thus the cyanobacterial blooms were avoided. In addition, the influence of the ultrasonic parameters on the algae removal or inhibition as well as the ultrasound influence on cellular physiological system was analyzed. The mechanism of algae removal and inhibition by the ultrasound was employed. Given the existed deficiencies in previous studies, the focus of follow-up study was prospected.