This paper introduces three successful engineering cases of algal bloom control in lakes and reservoirs conducted by a research group from Fudan University based on the theory of biomanipulation. The related knowledge and technological innovations, involving the concept of the inner-outer symbiosis pollution source and its amplifying effects, the significance of algal bloom control to treatment of eutrophic water in lakes and reservoirs, the synergies of the traditional and non-traditional biomanipulation technologies, the effects of sustainable bio-control of algae beginning from winter on the algal bloom control of eutrophic lakes and reservoirs, the suitable modes of stocking algivores, and control of the secondary pollution from manure of filter-feeding fish, are described.