In order to improve the informatization level of urban flood control and drainage dispatching and innovate flood regulation mode in China, an event-centered urban flood regulation mode was proposed, the basic idea was expounded, and the processes of event generation and classification, regulation plan, and event handling were analyzed and designed. With city D as an example, the implementation of the event-centered urban flood regulation mode was discussed. The preliminary application shows that the mode can adapt to the actual situation of urban flood regulation and effectively improve the urban flood management.