Based on the observational data of groundwater level in Hexi Corridor from 2009 to 2019, this study used the geostatistical method to investigate the spatial distribution characteristics of groundwater level in Hexi Corridor, and also used R/S analysis based on fractal theory to calculate the Hurst exponent of groundwater depth time series and to analyze the evolution trend of groundwater level. Results showed that the groundwater level in Hexi Corridor had a continuously declining trend from 2009 to 2019; the groundwater level in Hexi Corridor had the highest correlation with irrigated area, followed by population and groundwater supply; the groundwater level in Jinchang, Wuwei, Baiyin, and the central area of Jiuquan would continue to decline in the coming period, while the groundwater level in the western part of Jiuquan and most areas of Zhangye would not show obvious variation trends and would fluctuate randomly.