The information resource model for River Chief informatization system based on GIS grid was proposed. This model takes the river and lake system as the core, divides the sections according to the River Chief administrative region, forms the river and lake model, and designs the storage structure of each type of data directory, so that all kinds of data are associated with the main river and lake model object. In the meantime, the GIS spatial data objects of river and lake resources based on the river and lake model are formed by meshing the objects of river and lake resources under hierarchical jurisdiction according to the administrative division by the method of GIS spatial data processing. The spatial analysis function of GIS is used to automatically associate different types of data resources with river and lake resource objects in corresponding segments, so as to provide data services and support the operation of monitoring and supervision information of the whole River Chief system. This model was applied to Changsha River Chief system information management system, and realized the information working mode of river and lake management based on “Internet+”, which greatly improved the efficiency of River Chief system information work.