Based on the analysis of the connotation of high-quality development in the lower reaches of the Yellow River, a high-quality development evaluation index system was constructed from five dimensions of economic development, open cooperation, innovation-driven development, social livelihood, and ecological environment to calculate the high-quality development level in the lower reaches of the Yellow River from 2010 to 2017. Copulas function and grey correlation degree analysis method were used to quantitatively evaluate the correlation between water resources utilization and high-quality development in the lower reaches of the Yellow River. The results show that the overall level of high-quality development in the lower reaches of the Yellow River shows a steady upward trend with obvious differences in the level of high-quality development among different cities. Besides, there is a strong correlation between total water consumption and high-quality development level in the lower reaches of the Yellow River and cities with a higher level of high-quality development have a stronger degree of correlation. Overall, the correlation between industrial and living water consumption and high-quality development is slightly higher than that between total water consumption and agricultural water consumption and high-quality development.