Pearson correlation coefficient method was employed to analyze the best precipitation lag time at the monthly scale of each hydrological station in Mingshui spring area. According to the best precipitation lag time, the Pearson correlation coefficients of spring discharge and precipitation of each hydrological station from 2006 to 2013 were calculated at the ten-day scale and the daily scale, respectively. Thus the hydrological stations closely related to spring discharge were found out and the strong runoff zone in Mingshui spring area was identified. The results show that the best precipitation lag time of each station is 5 months. The precipitation changes of Mingshui Station, Yanjiayu Station and Xusheng Station are greatly consistent with the spring discharge, which have a relatively large impact on the spring discharge. The strong runoff zone of karst water-bearing medium in Mingshui spring area may exist at the location of three stations.