Along with the further implementation of “The Belt and Road Initiative” and the promotion of ChinaPakistan Economic Corridor(CPEC), it is foreseeable that the construction of CPEC may be faced with difficulties and challenges due to the differences between China and Pakistan in politics, economy, culture, religion, language, customs, environmental management system, environmental protection law, social management system and social management regulations. Then, CPEC is divided into western high mountain region, southeast coastal plain region, northern Kashmir region and Xinjiang region, China. Based on this, the paper discusses the social risks of different regions and different industries. The social risks of western high mountain region mainly include tribal obstacles and religious extremism. The social risks of southeast coastal plain region include the historical and cultural heritage and national park protection. The social risks of north Kashmir include transdispute areas, extremist threats, religious cultural differences and the protection of nature reserves. The social risks of Xinjiang region mainly include social problems caused by the problems of ethnic minorities and environment.