The structural characteristics of business model， market competition strategies and corporate performance are emerging issues in the field of innovation and strategy research. Based on the twodimensional attributes of business model capacity and business model tightness, this empirical research on 182 pharmaceutical listed companies found that appropriate business model strategies can help enterprises shape their value capacity space under the premise of cost leadership strategy and accumulate their value sealing ability under the guidance of differentiated strategy. The research confirmed that a good business model could lead to predictability of customer behavior and predictability of collaborator behavior, creating a unique strategic scenario for business development that enables companies to achieve or maintain high levels of performance.