Guiding social forces to participate in grassroots governance is one of the important contents of constructing a new pattern of grassroots social governance during the “14th Five-Year Plan”period in China. Social organizations have played a special role of “synergy”in participating in emergency management, especially in the governance of public health emergencies. How social organizations learn from crises in emergency situations, quickly realize business adjustment and environmental adaptation in crises, and cooperate with government departments and professional organizations to form a collaborative governance mechanism to deal with emergencies are important concerns for research on emergency management and social governance. Based on the crisis learning theory and collaborative governance theory, an analytical framework was established to study the “service-oriented” and “resource-oriented” crisis learning collaborative governance mechanisms of Social Work Center X and Foundation Q, which participated in the emergency response of public health emergencies in City B. The study found that timely adjustment of the multi-subject leadership mechanism is the prerequisite for social organizations to adapt to the emergency conditions of public health events. Adhering to demand-oriented and accurate docking of resources is the key to coordinated prevention and control. Information-based crisis learning and role positioning can effectively improve the efficiency of emergency response. At present, the coordination mechanism is not perfect, the response speed of government functional departments is not fast enough, the relevant long-term working mechanism is not perfect and other problems will affect the positive interaction of multiple subjects and the effective allocation of resources in emergency management. Based on this, in the aspect of system construction, it is necessary to establish the emergency response mechanism of social organizations to improve the response ability of government and social cooperation in public crisis. In the aspect of functional development, we should make good use of the professional advantages of social organizations, and form a three-way joint emergency management and governance pattern of “government-market-society”.